Phi X 174 slice

Structure and Potential of the CRISPR-Cas 10 System

Abstract By Brigette Corder, Sterling Ericsson, and Taylor Uhlir The CRISPR-Cas systems are a new and exciting tool for research and scientific discovery. Here we discuss and compare the various CRISPR-Cas systems and report current uses for these systems by concentrating a principal spotlight on CRISPR-Cas 10. From CRISPR’s rudimentary beginnings in the form of […]

Compact bone - ground cross section

Dead CRISPR-Cas9 Upgraded To Treat Genetic Disorders With No Gene Editing

Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]

Mouse embryo

CRISPR Discovers Embryo Gene’s Fate And The Futility Of Mice Models

The field of embryology continues to be one with more mysteries than answers. Since it is difficult in many countries around the world to work directly with human embryos, animal models are often the best we can do. To a certain extent, stem cells allow us to at least observe the earliest stages of multicellular […]

Neuron-matrix

RNA-Targeting CRISPR-Cas9 Cures Neurological Diseases In Living Cells

The research into new forms of CRISPR seems never-ending. It is an ongoing goal of scientists around the world to expand scientific knowledge on different kinds of CRISPR and also creating newfound capabilities for the existing varieties. Since the greater the flexibility of the tools available to science, the more treatments and medicines that can […]

SK8-18-2 human derived cells, fluorescence microscopy (29942101073)

An Official CRISPR Library For Genetic Silencing Guidance

While genetic modification tools like CRISPR have opened up new doors to making changes to genomes, it is still not as simple of a task as putting the CRISPR complex into a cell and having it go to work. It first must be given a target DNA sequence to focus on and, in most cases, […]

Rat primary cortical neuron culture, deconvolved z-stack overlay (30614937102)

CRISPR-Cas9 Allows Photographic Imaging Of Genes In Live Cells

Imaging cellular processes has always been difficult. With biotechnology, we have been able to use marker genes like green fluorescent protein (GFP) to follow the activities of individual cells, but that is a far cry from interior mechanisms within a cell. Since the dawn of the field, technology has advanced so that fluorescent microscopy has […]