Neuron-matrix

RNA-Targeting CRISPR-Cas9 Cures Neurological Diseases In Living Cells

The research into new forms of CRISPR seems never-ending. It is an ongoing goal of scientists around the world to expand scientific knowledge on different kinds of CRISPR and also creating newfound capabilities for the existing varieties. Since the greater the flexibility of the tools available to science, the more treatments and medicines that can […]

SK8-18-2 human derived cells, fluorescence microscopy (29942101073)

An Official CRISPR Library For Genetic Silencing Guidance

While genetic modification tools like CRISPR have opened up new doors to making changes to genomes, it is still not as simple of a task as putting the CRISPR complex into a cell and having it go to work. It first must be given a target DNA sequence to focus on and, in most cases, […]

Tribolium castaneum87-300

CRISPR Gene Drive Resistance Due To Inbreeding And Mutations

In a previous article, we discussed how CRISPR is not almighty and that organisms can evolve resistance to the changes made to their genome. The simplest method for them to accomplish this is just to mutate the changed gene back to what it was before or just stop its function altogether. If the change made […]

Rat primary cortical neuron culture, deconvolved z-stack overlay (30614937102)

CRISPR-Cas9 Allows Photographic Imaging Of Genes In Live Cells

Imaging cellular processes has always been difficult. With biotechnology, we have been able to use marker genes like green fluorescent protein (GFP) to follow the activities of individual cells, but that is a far cry from interior mechanisms within a cell. Since the dawn of the field, technology has advanced so that fluorescent microscopy has […]

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CRISPR: An In-Depth Primer On All Its Varieties

A Historical Viewpoint The Explosion Onto The Public Stage For those focused on how history will favor the uncovering of CRISPR and the miraculous developments that have and will spawn from it, the first thing to note is that the idea and research into the technology started several years prior to its explosion into the […]

Aedes aegypti adult overies

CRISPR Is Not Immune To The Development Of Resistance Genes

Depending on your point of view about biotechnology, recent revelations about the effects of CRISPR on organisms could be good or bad. As a science writer for Bioscription, I take the news as a little of both. Gene Drives So, what happened? Recent research between the University of Kansas and Cornell University has discovered that […]

Sow and five piglets

PRRS-Resistant Pigs Produced Using CRISPR-Cas9 For DNA Deletion

Another success of CRISPR-Cas9 has just been announced with the production of pigs that are likely resistant to one of the scourges of porcine husbandry, Porcine Reproductive and Respiratory Syndrome (PRRS). This viral disease infects thousands of pigs worldwide and is highly fatal, especially for pregnant sows or young pigs. As for the industry itself, […]

Macular Degeneration

The New Smallest Version of CRISPR-Cas9 Has Been Discovered

The other day on Bioscription, we discussed the South Korean Institute for Basic Science (IBS) and their work with CRISPR-Cpf1 in soybeans. Today, the same organization has released a study on a new form of CRISPR-Cas9 that they isolated from Campylobacter jejuni. This resulted in the acronym CjCas9 for it. A Problem Of Size A […]