Specificity and efficiency in targeting is one of the hallmark aims of any CRISPR system. The ability to edit a genome is useless without the capability to target a particular sequence and reliably alter it. Thus, work has been perpetually ongoing in the hunt to find better CRISPR systems or to even design one from […]
The central dogma of molecular biology and genetics is pretty straightforward. You take DNA, then you transcribe the desired gene into RNA (usually mRNA) and, once outside of the nucleus, you translate that RNA using ribosomes into amino acids that then form proteins. Those proteins then do the actual function that their original genetic encoding […]