Neuron cluster

New CRISPR Tool Manipulates RNA Splicing to Control the Transcriptome

Control over the genome and the epigenome has continued to be a prime focal point for the fields of science. New genome editing technologies and their related epigenetic tools has only exacerbated this spotlight. However, there are other areas of expression control that are available and some techniques, such as RNA interference (RNAi), seem to […]

Neuronal explosion

Stem Cells Modified To Sensory Neurons May Help Treat Paralysis

Our nervous system directs most of our body’s mechanisms without us being away of it. Motor neurons are involved in moving parts of our body, sensory neurons give us each of our major secondary senses like our sense of pain or temperature, and interneurons connect all the other neurons together into a combined whole that […]

Compact bone - ground cross section

Dead CRISPR-Cas9 Upgraded To Treat Genetic Disorders With No Gene Editing

Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]

Asco Candida albicans

Gene Editing Tool Allows Dozens Of Modifications Without DNA Cleavage

The benefits of modern gene editing techniques and tools come with some downsides. While the precision of new and improved CRISPR systems is continually on the rise, there are some fundamental aspects of the tools that scientists have long wished we could work around, in order to reduce even the most minimal risk of off-target […]

Hippocampal neurons in culture

Buildup of Toxic Parkinson’s Protein Averted With CRISPR Screening

Decoding the impact of genetic manipulation is a convoluted task. When it comes to investigating multi-layered diseases like Parkinson’s, it is fully expected that a whole host of genes in sequence or applied in simultaneity are used to promote onset of the disease. The process of figuring out which genes are involved or, conversely, which […]


A Nematode Neuron Gene May Hold Key To Treating Neurodegenerative Disorders

Neurodegenerative disease research has long been focused on understanding the underlying genes and molecules involved in the breakdown of mental function. But it is a multi-faceted process, involving some of the most complicated cell types in the human body. The main focal point has been on determining how the diseases progress and what can be […]

Virus created with blender 249b 001

The Relaxed System of CRISPR-Cas10 Is Deadly To Mutated Viruses

The specificity found within the mechanisms of the CRISPR system can be both a boon and a bane. Thanks to things like the PAM sequence, CRISPR-Cas9 has found itself as a useful tool to accurately target desired gene sequences at an unparalleled level. No other gene editing technology can really come close to matching the […]


RNA-Targeting CRISPR-Cas9 Cures Neurological Diseases In Living Cells

The research into new forms of CRISPR seems never-ending. It is an ongoing goal of scientists around the world to expand scientific knowledge on different kinds of CRISPR and also creating newfound capabilities for the existing varieties. Since the greater the flexibility of the tools available to science, the more treatments and medicines that can […]