Mapping Genetic Pathways With MAGIC CRISPR

While the effects of a singular gene and its protein output can be measured and quantified, many traits of organisms are part of far more complex regulatory pathways involving dozens of genes that turn on and off different systems. Mapping out how these pathways interact and what genes make them up has been a key […]

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CRISPR RNP Alteration Proves Key To Avoiding Human Immune Response

Gene editing itself has truly just been the start of the modern biotechnological revolution. As time has passed, the nuance of capability with tools like CRISPR has evolved to not only be more precise, but to also have additional options beyond just additions or deletions of genes. New versions have included things like inducing point […]

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CRISPR Cas12 Used To Make An Accurate Viral Infection Detector

When it comes to gene editing technologies like CRISPR, the initial applications were focused around just that, the capability to edit and alter gene sequences. The main efforts after were to enhance the specificity of this activity and to improve further what could be changed. But in recent years we’ve begun to see an expansion […]

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An Official CRISPR Library For Genetic Silencing Guidance

While genetic modification tools like CRISPR have opened up new doors to making changes to genomes, it is still not as simple of a task as putting the CRISPR complex into a cell and having it go to work. It first must be given a target DNA sequence to focus on and, in most cases, […]

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CRISPR Gene Drive Resistance Due To Inbreeding And Mutations

In a previous article, we discussed how CRISPR is not almighty and that organisms can evolve resistance to the changes made to their genome. The simplest method for them to accomplish this is just to mutate the changed gene back to what it was before or just stop its function altogether. If the change made […]