Human Cell

Targeted RNA Changes With New CRISPR Tool Subvert Genetic Concerns

Specificity and efficiency in targeting is one of the hallmark aims of any CRISPR system. The ability to edit a genome is useless without the capability to target a particular sequence and reliably alter it. Thus, work has been perpetually ongoing in the hunt to find better CRISPR systems or to even design one from […]

Smallpox CAM

A Controversy of Biosafety and Bioethics: Horsepox and the Risks of Smallpox

The topic has been raised time and again over the years, especially with the advent of medical biotechnology and the capability to reconstruct genomes wholecloth. Even if science has the capability to make something, should it? Smallpox In The Room In this case and in several prior instances, the discussion has been about the reconstruction […]

Tribolium castaneum87-300

CRISPR Gene Drive Resistance Due To Inbreeding And Mutations

In a previous article, we discussed how CRISPR is not almighty and that organisms can evolve resistance to the changes made to their genome. The simplest method for them to accomplish this is just to mutate the changed gene back to what it was before or just stop its function altogether. If the change made […]

A fly's first breath 1

Why Don’t Damaging Mutations Kill Off Humanity And Complex Life?

How is humanity still alive? How is most complex life still going in the first place? Biologically speaking, the number of genetic mutations we have with every generation that results in a negative effect should have wiped us all out. Simple Processes Natural selection as a random process and the error rate in our own […]

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CRISPR: An In-Depth Primer On All Its Varieties

A Historical Viewpoint The Explosion Onto The Public Stage For those focused on how history will favor the uncovering of CRISPR and the miraculous developments that have and will spawn from it, the first thing to note is that the idea and research into the technology started several years prior to its explosion into the […]

Yeast membrane proteins

The Scientific Creation of a Fully Synthetic Living Organism

Progress continues on the Synthetic Yeast Project, an international scientific initiative that aims to build a yeast genome out of completely synthetic chromosomes. The latest update involves seven papers published together in the journal Science detailing the five pre-designed chromosomes that have been successfully swapped into the genome of yeast. The model organism S. cerevisiae […]

4cell embryo

Creating An Artificial Embryo Using Genetically Modified Stem Cells

Cloning is a difficult process. Even with modern technologies, the best we can do is generate matching organs from a person’s stem cells, but this itself is still tricky to accomplish. Actually cloning a whole organism? We’re nowhere near where we need to be. The Troubles of Cloning The main problem inherent in this process […]

Scanning electron micrograph of phagocytosis of a dead yeast particle

A Tenet Of Evolutionary Biology May Be Completely Wrong

Not every tenet of science is set in stone. That’s often been seen in fields like physics and astronomy over the past few decades, where huge innovations and discoveries have been made. But biology isn’t isolated from these sorts of findings. Today’s topic of discussion is new research that calls one of the tenets of […]