E15.5 mouse embryonic testes

Genetic Barcodes In Mice Allow CRISPR To Map Body Cell Development

“If all you have is a hammer, everything looks like a nail” is how the saying goes. But does that have to be true? A hammer can actually be a quite versatile instrument and, with some insight and ingenuity, be put to tasks that would previously have been thought outside of its purview. A hammer […]

Group A Streptococcus Bacteria on Human Neutrophil (8517040030)

CRISPR-Polymerase Fusion Makes A Forced Mutation And Evolution Tool

The past five or so years has been a bit of a roller-coaster for any field that dabbles in genetics. The advancements the scientific community has made in such a short time frame are nothing less than extraordinary and things only seem to be accelerating from here on out. And the single piece of technology […]

Potatovirusy

Plant Pathogenic Viruses: An Overview of Current Biotechnology Research

Pathogens are a broad field of research. To many, different species and even kingdoms of pathogens must be treated with separate hands, while others feel they are similar enough as to be dealt with together. Bacteria and viruses make up the bulk of this argument and, as with many things, the true answer appears to […]

Early embryonic development of Encarsia pergandiella. Nature as art or vice versa?

Mapping Cell Lineages Using CRISPR Cas9-Based Genetic Scarring

There are a number of errors that can happen when an organism develops from an embryo to an adult. A single missing cell or a cell out of place can have catastrophic results for the matured individual. Even a slightly altered rate of cell division at such an early stage is more likely to cause […]

Neuron cluster

New CRISPR Tool Manipulates RNA Splicing to Control the Transcriptome

Control over the genome and the epigenome has continued to be a prime focal point for the fields of science. New genome editing technologies and their related epigenetic tools has only exacerbated this spotlight. However, there are other areas of expression control that are available and some techniques, such as RNA interference (RNAi), seem to […]

HIV-budding-Color

CRISPR RNP Alteration Proves Key To Avoiding Human Immune Response

Gene editing itself has truly just been the start of the modern biotechnological revolution. As time has passed, the nuance of capability with tools like CRISPR has evolved to not only be more precise, but to also have additional options beyond just additions or deletions of genes. New versions have included things like inducing point […]

Influenza virus particle color

CRISPR Cas12 Used To Make An Accurate Viral Infection Detector

When it comes to gene editing technologies like CRISPR, the initial applications were focused around just that, the capability to edit and alter gene sequences. The main efforts after were to enhance the specificity of this activity and to improve further what could be changed. But in recent years we’ve begun to see an expansion […]

Phi X 174 slice

Structure and Potential of the CRISPR-Cas 10 System

Abstract By Brigette Corder, Sterling Ericsson, and Taylor Uhlir The CRISPR-Cas systems are a new and exciting tool for research and scientific discovery. Here we discuss and compare the various CRISPR-Cas systems and report current uses for these systems by concentrating a principal spotlight on CRISPR-Cas 10. From CRISPR’s rudimentary beginnings in the form of […]

Compact bone - ground cross section

Dead CRISPR-Cas9 Upgraded To Treat Genetic Disorders With No Gene Editing

Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]