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Tumors Targeted In Novel Cisgenic CAR T-Cell Cancer Immunotherapy

The fight against the many forms of cancer has been a long and ongoing battle, with each different type requiring a novel and targeted solution to defeat. Generalized treatments have arisen over time, with the likes of CAR T-cell therapy, but there are still numerous hurdles depending on the cancer being dealt with. Before that […]

Chickpea Genes May Give New Life To Brassica Against Fungal Blight

There are, always, too many pathogens in the world. Often too many to catalog and keep track of and they are constantly changing, whether bacterial, viral, fungal, or even other options. When it comes to plants and agricultural output, the worst kinds of pathogens are those that can infect a variety of important crops grown […]

Bound Chromatin Blocking CRISPR Genetic Engineering Broken Open

Scientists and scientific publications often discuss CRISPR as a tool that, once inserted successfully into a cell, just gets to work on modifying the host cell genome. Its efficiency and accuracy may vary, but it is often thought of in conversation as a highly effective gene modifying device. That as it turns out is only […]

Plants Copy Nematode Pheromones To Repel Infestations

Plants never cease to reveal their unique and astonishing methods of protecting themselves from pathogens. Here on Bioscription we’ve previously discussed the topic of the pathogen-associated molecular pattern (PAMP) system and how it allows plants to uptake and conserve important foreign molecules for future immune system response. It is, in many ways, similar to the […]

Mapping Genetic Pathways With MAGIC CRISPR

While the effects of a singular gene and its protein output can be measured and quantified, many traits of organisms are part of far more complex regulatory pathways involving dozens of genes that turn on and off different systems. Mapping out how these pathways interact and what genes make them up has been a key […]

Serrated wrack, red hornweed and other algae in Govik

Horizontally Transferred Genes Make Up 1% of Red Algae Genomes

The importance of horizontal gene transfer (HGT) is likely understated in science. It was discussed only rarely in the past and, despite its current popularity and resurgence in relevance today, it continues to retain further secrets within the natural world that we have yet to uncover. We now openly know and have showcased over the […]

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Directed Evolution of Plants Via CRISPR DNA Breakage and Mutagenesis

If one is trying to find new and unique traits and abilities in any organism, then the regular span of generations takes far too long in the natural world. Instead of relying on evolution by natural selection, directed evolution by human hands works much better and can be accelerated in multiple ways. So far, the […]

Plant and Insect Viruses Act Symbiotically In Host Infection

When dealing with pathogens of plants, it is those of the viral kind in conjunction with their vector pests that can prove to be the biggest threats. Aphids, especially, are known for transmitting dozens of dangerous viral diseases while also themselves managing to kill a host plant outright through sucking up too much sap. Therefore, […]

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Motif Removal Gives DNA Invisibility To Bacterial Detection Systems

While genetic modification technologies have been expanding rapidly in the biological and medical spheres, there is an obvious limitation in how this sort of research is applied. For the microscopic level and the macro beyond it, only a select number of organisms have proven to be amenable to such modification techniques. Others have either shown […]