Bound Chromatin Blocking CRISPR Genetic Engineering Broken Open

Scientists and scientific publications often discuss CRISPR as a tool that, once inserted successfully into a cell, just gets to work on modifying the host cell genome. Its efficiency and accuracy may vary, but it is often thought of in conversation as a highly effective gene modifying device. That as it turns out is only […]

Neuron cluster

New CRISPR Tool Manipulates RNA Splicing to Control the Transcriptome

Control over the genome and the epigenome has continued to be a prime focal point for the fields of science. New genome editing technologies and their related epigenetic tools has only exacerbated this spotlight. However, there are other areas of expression control that are available and some techniques, such as RNA interference (RNAi), seem to […]

Müürlooga õie stigma

Epimutagenesis Controls DNA Methylation To Reveal Hidden Plant Traits

Properly breeding a plant for the traits you want is hard. It requires hundreds of plants and hundreds of cross-breeding attempts between them to obtain desired traits, isolate them, and cross them into more vigorous cultivars with other wanted traits. That was how it was done for most of human history and it’s a long, […]

Compact bone - ground cross section

Dead CRISPR-Cas9 Upgraded To Treat Genetic Disorders With No Gene Editing

Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]