3D still showing tumor

Tumors Targeted In Novel Cisgenic CAR T-Cell Cancer Immunotherapy

The fight against the many forms of cancer has been a long and ongoing battle, with each different type requiring a novel and targeted solution to defeat. Generalized treatments have arisen over time, with the likes of CAR T-cell therapy, but there are still numerous hurdles depending on the cancer being dealt with. Before that […]

Bound Chromatin Blocking CRISPR Genetic Engineering Broken Open

Scientists and scientific publications often discuss CRISPR as a tool that, once inserted successfully into a cell, just gets to work on modifying the host cell genome. Its efficiency and accuracy may vary, but it is often thought of in conversation as a highly effective gene modifying device. That as it turns out is only […]

Cancer cells (1)

Photoresponsive Nanoparticles And CRISPR Activation To Treat Cancer

When it comes to using CRISPR on a broad scale, different types of applications have to be utilized for different systems. If modifying bacterial genomes are the focus, then a viral vector to get the CRISPR complex into the cell is efficient enough for most purposes. But on multicellular organisms, there can be a number […]

Albinoaxolotl3

Axolotl Tail Regrowth Holds Key To Spinal Cord Regeneration

For all the advances we’ve made in medical science toward treatment of dangerous disorders and diseases, along with recent announcements such as a secondary success in long-term HIV remission, there are still plenty of conditions that we have a long way to go toward any sort of viable treatment. Spinal cord injuries are one such […]

Vessels (248 18) Cross-section

Using Biomaterials To Make Transplantable Human Blood Vessel Systems

When severe injuries occur, there can often be damage to skin, tissues, and organs. Depending on the extent of that damage, replacements can often be required. It has only been in recent decades that medical technologies have advanced far enough for things like skin grafts and organ replacements to have become viable and at a […]

18110_lores

Transposons: A History of Their Discovery and Their Viral Connections

As science has continued its investigation into the inner workings of biology and biological systems on the molecular level, we have managed to unearth more and more complexity in the relationships within not only our own body, but in the world around us. Every organism has a symbiotic and antagonistic relationship with its surroundings, with […]

Mouse litter

Genetically Modified Stem Cells Allow Mice Born With Same-Sex Parents

Research into sexual embryonic development and the forms of offspring progeneration has long been a source of study to determine yet another facet to early formation of the embryo. Mammals are a bit special when it comes to the topic of genetic development of the egg cell. All of our animal cousins among the reptiles, […]

E15.5 mouse embryonic testes

Genetic Barcodes In Mice Allow CRISPR To Map Body Cell Development

“If all you have is a hammer, everything looks like a nail” is how the saying goes. But does that have to be true? A hammer can actually be a quite versatile instrument and, with some insight and ingenuity, be put to tasks that would previously have been thought outside of its purview. A hammer […]