Caenorhabditis elegans DAPI

Transgenic Gene Knockouts May Allow Autophagy To Extend Lifespans

The cellular processes of aging are complicated and varied. There are both genetic and mechanical components that all have an ultimate effect on a person as they age and reach the period of senescence. But it is not only humans and our medical community that are attempting to arrest this mechanism, the cells themselves also […]

Neuron cluster

New CRISPR Tool Manipulates RNA Splicing to Control the Transcriptome

Control over the genome and the epigenome has continued to be a prime focal point for the fields of science. New genome editing technologies and their related epigenetic tools has only exacerbated this spotlight. However, there are other areas of expression control that are available and some techniques, such as RNA interference (RNAi), seem to […]

Neuronal explosion

Stem Cells Modified To Sensory Neurons May Help Treat Paralysis

Our nervous system directs most of our body’s mechanisms without us being away of it. Motor neurons are involved in moving parts of our body, sensory neurons give us each of our major secondary senses like our sense of pain or temperature, and interneurons connect all the other neurons together into a combined whole that […]

Hippocampal neurons in culture

Buildup of Toxic Parkinson’s Protein Averted With CRISPR Screening

Decoding the impact of genetic manipulation is a convoluted task. When it comes to investigating multi-layered diseases like Parkinson’s, it is fully expected that a whole host of genes in sequence or applied in simultaneity are used to promote onset of the disease. The process of figuring out which genes are involved or, conversely, which […]

Neuron-SEM-2

A Nematode Neuron Gene May Hold Key To Treating Neurodegenerative Disorders

Neurodegenerative disease research has long been focused on understanding the underlying genes and molecules involved in the breakdown of mental function. But it is a multi-faceted process, involving some of the most complicated cell types in the human body. The main focal point has been on determining how the diseases progress and what can be […]

Neuron-matrix

RNA-Targeting CRISPR-Cas9 Cures Neurological Diseases In Living Cells

The research into new forms of CRISPR seems never-ending. It is an ongoing goal of scientists around the world to expand scientific knowledge on different kinds of CRISPR and also creating newfound capabilities for the existing varieties. Since the greater the flexibility of the tools available to science, the more treatments and medicines that can […]

Smoking Leads to Weight Loss? Fact-Checking With Nematodes

Smoking has long had a cultural history associated with weight loss. Even without understanding the biochemistry involved, ancient peoples and cultures all the way up to modern times have associated smoking with appetite suppression. Going off smoking has then often resulted in huge weight gain, related to a higher caloric intake afterward and a slower […]

Let’s Make A Brain: Stem Cells, CRISPR, and Cerebral Organoids

Perfectly mapping and even regrowing parts of a brain has long been something only considered to be a thing in science fiction. The technology has always seemed like it was centuries away from ever becoming a reality. But, day by day, researchers continue to develop new techniques and methods that push the boundaries of what […]