VariousPills

Pharmacogenomics: Genetics As Personalized Medicine

With the great strides and advances in medicine that have been brought to the stage in the past several decades and especially in the past ten years, there has been a shift in focus and perspective in the pharmacological community. Previously, the task had been to develop medicines to treat conditions big and small or, […]

Afghan Hound blond portrait

Cloning of Clones and No Early-Onset Age Disorders for Clones

Cloning has long been a topic fraught with controversy and vocalized concern about where the technology would lead. While we still grapple with these ideas to this very day, the science itself continues to move forward toward a better understanding of how cloning works and what repercussions biologically it might have. Or might not have, […]

Asco Candida albicans

Gene Editing Tool Allows Dozens Of Modifications Without DNA Cleavage

The benefits of modern gene editing techniques and tools come with some downsides. While the precision of new and improved CRISPR systems is continually on the rise, there are some fundamental aspects of the tools that scientists have long wished we could work around, in order to reduce even the most minimal risk of off-target […]

Proliferative response induced by a tumor promoter in the epidermis of a wild-type mouse - image.pbio.v11.i07.g001

Gene Therapy And Stem Cells Restore 80% of Child’s Skin

Sometimes doctors are able to accomplish the most miraculous of surgeries using top of the line technology. Treatments with an incredibly low chance of success and with a high risk of death. Successes that likely will not be possible to do again in the near future, even with other patients with the same condition. That […]

Human Cell

Targeted RNA Changes With New CRISPR Tool Subvert Genetic Concerns

Specificity and efficiency in targeting is one of the hallmark aims of any CRISPR system. The ability to edit a genome is useless without the capability to target a particular sequence and reliably alter it. Thus, work has been perpetually ongoing in the hunt to find better CRISPR systems or to even design one from […]

Проводящий пучок Pteridium aquilinum

Plants Fight Flooding From Climate Change With Root Bending

Recent events shed a light on what we possibly face in the future, as hurricanes and other weather events become more severe due to the increased energy capacity of the atmosphere from greenhouse gas influx. The colloquial term for this process is climate change. And scientists are hard at work on finding ways to mitigate […]

Hippocampal neurons in culture

Buildup of Toxic Parkinson’s Protein Averted With CRISPR Screening

Decoding the impact of genetic manipulation is a convoluted task. When it comes to investigating multi-layered diseases like Parkinson’s, it is fully expected that a whole host of genes in sequence or applied in simultaneity are used to promote onset of the disease. The process of figuring out which genes are involved or, conversely, which […]

Embryonic smooth muscle cell

Correcting Muscular Dystrophy With CRISPR and Gold Nanoparticles

Being one of the earliest focused upon diseases for CRISPR to treat other than retinitis, Duchenne muscular dystrophy has seen a lot of scientific effort be put into finding a cure or at least a palliative treatment to restore some amount of strength. Previous attempts have involved various types of viral vectors to help remove […]

Mouse embryo

CRISPR Discovers Embryo Gene’s Fate And The Futility Of Mice Models

The field of embryology continues to be one with more mysteries than answers. Since it is difficult in many countries around the world to work directly with human embryos, animal models are often the best we can do. To a certain extent, stem cells allow us to at least observe the earliest stages of multicellular […]

Neuron-SEM-2

A Nematode Neuron Gene May Hold Key To Treating Neurodegenerative Disorders

Neurodegenerative disease research has long been focused on understanding the underlying genes and molecules involved in the breakdown of mental function. But it is a multi-faceted process, involving some of the most complicated cell types in the human body. The main focal point has been on determining how the diseases progress and what can be […]