Müürlooga õie stigma

Epimutagenesis Controls DNA Methylation To Reveal Hidden Plant Traits

Properly breeding a plant for the traits you want is hard. It requires hundreds of plants and hundreds of cross-breeding attempts between them to obtain desired traits, isolate them, and cross them into more vigorous cultivars with other wanted traits. That was how it was done for most of human history and it’s a long, […]

HIV-budding-Color

CRISPR RNP Alteration Proves Key To Avoiding Human Immune Response

Gene editing itself has truly just been the start of the modern biotechnological revolution. As time has passed, the nuance of capability with tools like CRISPR has evolved to not only be more precise, but to also have additional options beyond just additions or deletions of genes. New versions have included things like inducing point […]

Influenza virus particle color

CRISPR Cas12 Used To Make An Accurate Viral Infection Detector

When it comes to gene editing technologies like CRISPR, the initial applications were focused around just that, the capability to edit and alter gene sequences. The main efforts after were to enhance the specificity of this activity and to improve further what could be changed. But in recent years we’ve begun to see an expansion […]

Scanning electron micrograph of Methicillin-resistant Staphylococcus aureus (MRSA) and a dead Human neutrophil - NIAID

9 New Bacterial Defense Systems May Herald CRISPR-Like Discovery

Going back to the beginning of CRISPR feels like traveling through a time portal. The gene editing technology has become so ingrained in our lives, in scientific literature and the news, that it feels like it’s been a decade or two already since we started using it. It comes as a bit of a shock […]

Phi X 174 slice

Structure and Potential of the CRISPR-Cas 10 System

Abstract By Brigette Corder, Sterling Ericsson, and Taylor Uhlir The CRISPR-Cas systems are a new and exciting tool for research and scientific discovery. Here we discuss and compare the various CRISPR-Cas systems and report current uses for these systems by concentrating a principal spotlight on CRISPR-Cas 10. From CRISPR’s rudimentary beginnings in the form of […]

Compact bone - ground cross section

Dead CRISPR-Cas9 Upgraded To Treat Genetic Disorders With No Gene Editing

Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]

Asco Candida albicans

Gene Editing Tool Allows Dozens Of Modifications Without DNA Cleavage

The benefits of modern gene editing techniques and tools come with some downsides. While the precision of new and improved CRISPR systems is continually on the rise, there are some fundamental aspects of the tools that scientists have long wished we could work around, in order to reduce even the most minimal risk of off-target […]

Human Cell

Targeted RNA Changes With New CRISPR Tool Subvert Genetic Concerns

Specificity and efficiency in targeting is one of the hallmark aims of any CRISPR system. The ability to edit a genome is useless without the capability to target a particular sequence and reliably alter it. Thus, work has been perpetually ongoing in the hunt to find better CRISPR systems or to even design one from […]

Hippocampal neurons in culture

Buildup of Toxic Parkinson’s Protein Averted With CRISPR Screening

Decoding the impact of genetic manipulation is a convoluted task. When it comes to investigating multi-layered diseases like Parkinson’s, it is fully expected that a whole host of genes in sequence or applied in simultaneity are used to promote onset of the disease. The process of figuring out which genes are involved or, conversely, which […]