SK8-18-2 human derived cells, fluorescence microscopy (29942101073)

An Official CRISPR Library For Genetic Silencing Guidance

While genetic modification tools like CRISPR have opened up new doors to making changes to genomes, it is still not as simple of a task as putting the CRISPR complex into a cell and having it go to work. It first must be given a target DNA sequence to focus on and, in most cases, […]

Neural Stem Cells and Growth Hormone Receptor

Using CRISPR Proteins To Record A Video Clip Into Bacterial Genomes

Analyzing biological phenomena is often difficult to accomplish, even with modern technology. In many cases, for the actions of small biomolecules and other hard to see functioning parts of a cell, we can only take snapshots that tell us a moment in time. But that’s not all that helpful for understanding the actions of enzymes […]

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First CRISPR Gene-Edited Crop Expected By 2020

Science in the field of biotechnology is changing rapidly and the effects of new technology is rippling out to affect many other parts of biology and medicine as a whole. It cannot be overstated how much of a revolution CRISPR tools have been and continue to be to dozens of scientific fields. While it may […]

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CRISPR Gene Drive Resistance Due To Inbreeding And Mutations

In a previous article, we discussed how CRISPR is not almighty and that organisms can evolve resistance to the changes made to their genome. The simplest method for them to accomplish this is just to mutate the changed gene back to what it was before or just stop its function altogether. If the change made […]

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Resurrecting Ancient Proteins To Fight Back Against Modern Viruses

Viruses have a variety of tactics they employ in their attacks on bacteria, plants, and animals like us. Their ultimate goal is to hijack the systems of the cell and convert them into producing more of themselves. Some viruses simply reconfigure construction molecules to directly make viral parts, others insert their own viral genes into […]

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A New Class of CRISPR Detailed and Its Variants Discovered

Revelations on new types of CRISPR classes and proteins continue to be found with every new month of research. This isn’t a surprising fact, as CRISPR is a system that has been, possibly independently, developed among a vast swath of single celled life. There are different versions of such systems all over the place and […]

Rat primary cortical neuron culture, deconvolved z-stack overlay (30614937102)

CRISPR-Cas9 Allows Photographic Imaging Of Genes In Live Cells

Imaging cellular processes has always been difficult. With biotechnology, we have been able to use marker genes like green fluorescent protein (GFP) to follow the activities of individual cells, but that is a far cry from interior mechanisms within a cell. Since the dawn of the field, technology has advanced so that fluorescent microscopy has […]

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CRISPR: An In-Depth Primer On All Its Varieties

A Historical Viewpoint The Explosion Onto The Public Stage For those focused on how history will favor the uncovering of CRISPR and the miraculous developments that have and will spawn from it, the first thing to note is that the idea and research into the technology started several years prior to its explosion into the […]

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Using Genetically Modified Ants To Figure Out Just How Ants Work

Ants are fascinating. As examples of highly social, structured, and often single-minded species, ants easily pique the interest of biologists and even scientists as a whole. Similar to bees, their colony structure exists as highly divergent from the rest of the multicellular life in the world. Most of it, at least. They can be viewed, […]

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CRISPR Is Not Immune To The Development Of Resistance Genes

Depending on your point of view about biotechnology, recent revelations about the effects of CRISPR on organisms could be good or bad. As a science writer for Bioscription, I take the news as a little of both. Gene Drives So, what happened? Recent research between the University of Kansas and Cornell University has discovered that […]