The cellular processes of aging are complicated and varied. There are both genetic and mechanical components that all have an ultimate effect on a person as they age and reach the period of senescence. But it is not only humans and our medical community that are attempting to arrest this mechanism, the cells themselves also […]
Control over the genome and the epigenome has continued to be a prime focal point for the fields of science. New genome editing technologies and their related epigenetic tools has only exacerbated this spotlight. However, there are other areas of expression control that are available and some techniques, such as RNA interference (RNAi), seem to […]
The ability to make stem cells from other cell types has largely been a recent phenomenon. It took a huge amount of research and testing to get to that point and, even today, it requires a complex cocktail of chemicals to induce the needed genetic and epigenetic changes that revert a cell to its infancy. […]
Our nervous system directs most of our body’s mechanisms without us being away of it. Motor neurons are involved in moving parts of our body, sensory neurons give us each of our major secondary senses like our sense of pain or temperature, and interneurons connect all the other neurons together into a combined whole that […]
Deadly disease pandemics are one of the most feared occurrences for public and global health researchers. They dread the day that such a disease manages to grip hold of a major population and then proceeds to spread internationally overnight. In all likelihood, such a disease will either be new or will be a known disease […]
Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]
The benefits of modern gene editing techniques and tools come with some downsides. While the precision of new and improved CRISPR systems is continually on the rise, there are some fundamental aspects of the tools that scientists have long wished we could work around, in order to reduce even the most minimal risk of off-target […]
Decoding the impact of genetic manipulation is a convoluted task. When it comes to investigating multi-layered diseases like Parkinson’s, it is fully expected that a whole host of genes in sequence or applied in simultaneity are used to promote onset of the disease. The process of figuring out which genes are involved or, conversely, which […]
Neurodegenerative disease research has long been focused on understanding the underlying genes and molecules involved in the breakdown of mental function. But it is a multi-faceted process, involving some of the most complicated cell types in the human body. The main focal point has been on determining how the diseases progress and what can be […]
The specificity found within the mechanisms of the CRISPR system can be both a boon and a bane. Thanks to things like the PAM sequence, CRISPR-Cas9 has found itself as a useful tool to accurately target desired gene sequences at an unparalleled level. No other gene editing technology can really come close to matching the […]
