Not every genetic modification has to involve a violent cleaving of nucleotides to insert or remove sections of the genome. The most common form this type of change takes involves what are termed double-strand breaks (DSBs) and they have long been something that scientists have wanted to avoid if possible. You may remember us discussing […]
We think about them in a ton of different ways. Fungi can be a delicacy in food or they can be a deadly poison. They are beneficial mutualists with plants or harmful parasitic pests. But there is one more feature of theirs that has become more and more prominent in recent decades with the emergence […]
Cloning has long been a topic fraught with controversy and vocalized concern about where the technology would lead. While we still grapple with these ideas to this very day, the science itself continues to move forward toward a better understanding of how cloning works and what repercussions biologically it might have. Or might not have, […]
Sudden death syndrome is, as the name would suggest, a devastating disease. It first emerged in Arkansas in 1971 and has since spread across the US and even into South America by the 1990’s, causing heavy fatalities. The fungus that causes it, Fusarium virguliforme, can be considered the root of one of the most deadly […]
Sometimes doctors are able to accomplish the most miraculous of surgeries using top of the line technology. Treatments with an incredibly low chance of success and with a high risk of death. Successes that likely will not be possible to do again in the near future, even with other patients with the same condition. That […]
Specificity and efficiency in targeting is one of the hallmark aims of any CRISPR system. The ability to edit a genome is useless without the capability to target a particular sequence and reliably alter it. Thus, work has been perpetually ongoing in the hunt to find better CRISPR systems or to even design one from […]
Decoding the impact of genetic manipulation is a convoluted task. When it comes to investigating multi-layered diseases like Parkinson’s, it is fully expected that a whole host of genes in sequence or applied in simultaneity are used to promote onset of the disease. The process of figuring out which genes are involved or, conversely, which […]
Being one of the earliest focused upon diseases for CRISPR to treat other than retinitis, Duchenne muscular dystrophy has seen a lot of scientific effort be put into finding a cure or at least a palliative treatment to restore some amount of strength. Previous attempts have involved various types of viral vectors to help remove […]
Neurodegenerative disease research has long been focused on understanding the underlying genes and molecules involved in the breakdown of mental function. But it is a multi-faceted process, involving some of the most complicated cell types in the human body. The main focal point has been on determining how the diseases progress and what can be […]
With an ever increasing population and global interaction, trade between nations and people moving to and fro poses distinct risks to biosecurity concerns. Human diseases are obviously top of the list, but because they involve direct contamination by humans themselves with other humans, most medical organizations around the world have numerous measures in place to […]