Once upon a time, scientists thought genetics and genomes were fairly straightforward. A gene encodes a protein and that protein carries out the actions that cause physical, metabolic effects and even phenotypic effects visible to others. It was a direct and simple system, a functional way for something formed through natural selection to be built. […]
Control over the genome and the epigenome has continued to be a prime focal point for the fields of science. New genome editing technologies and their related epigenetic tools has only exacerbated this spotlight. However, there are other areas of expression control that are available and some techniques, such as RNA interference (RNAi), seem to […]
Specificity and efficiency in targeting is one of the hallmark aims of any CRISPR system. The ability to edit a genome is useless without the capability to target a particular sequence and reliably alter it. Thus, work has been perpetually ongoing in the hunt to find better CRISPR systems or to even design one from […]
Revelations on new types of CRISPR classes and proteins continue to be found with every new month of research. This isn’t a surprising fact, as CRISPR is a system that has been, possibly independently, developed among a vast swath of single celled life. There are different versions of such systems all over the place and […]
